Washington UniversitySchool of Medicine
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Fred Prior

Fred Prior

Lab Director & Research Associate Professor of Radiology

Office: East Building 3355
Tel: (314)747-0331
Fax: (314)362-6971

priorf@mir.wustl.edu

Education

B.A., Chemistry, Case Western Reserve University - 1974
M.A., Anthropology, Case Western Reserve University - 1976
M.S., Biomedical Engineering, Case Western Reserve University - 1984
Ph.D., Computer Science, Illinois Institute of Technology - 1992

Background

Fred Prior, Ph.D. (CS), MS (BME), MA (Anthro), BA (Chem) is the Director of the Electronic Radiology Laboratory of the Mallinckrodt Institute of Radiology, and a Research Associate Professor of Radiology, Washington University in Saint Louis School of Medicine. Dr. Prior has over 30 years of R&D experience focused mostly on the design of advanced medical information management and communication technologies. He has worked in a variety of R&D environments ranging from Silicon Valley startups to major multi-national corporations in the US and Europe. He has held senior management positions with Imatron, Siemens Medical Systems, Philips Medical System, Cemax-Icon and Eastman Kodak and was formerly a member of the faculty of the departments of Radiology, Neuroscience and Bioengineering at Penn State University College of Medicine.

Research Interests

Dr. Prior's personal research is in the areas of research information management and image and signal processing. He is currently leading a multi-disciplinary team to develop a quantitative CT-based biomarker for Charcot Neuroarthropathy and IT systems to manage multi-center imaging trials. In addition, he has an active collaboration looking at new ways to analyze and visualize EEG data.

Affiliations/Professional Studies

Institute of Electrical and Electronics Engineers (IEEE) - Senior Member
NCI CaBIG In Vivo Imaging Workspace - Subject Matter Expert
IEEE Transactions on Information Technology in Biomedicine - Associate Editor
US Centers for Disease Control - Consultation and Oversight for Conversion of NIOSH Pneumoconiosis Programs to Accept Digital Chest Images

Publications

  1. Lestrel PE, Kimbel WH, Prior FW, Fleischmann ML. Size and Shape of the Hominoid Distal Femur: Fourier Analysis. Am J Phy Anthro. 1997; 46(2):281-290.
  2. Prior FW, Nabijee KH. Information Management for Data Retrieval in a Picture Archive and Communication System.  J Digit Imaging. 1989; 2(3):170-176.
  3. Prior FW, Specifying DICOM Compliance for Modality Interfaces. RadioGraphics. 1993; 13:1381-1388, 1993.
  4. Bidgood WD, Horii SC, Prior FW, Van Syckle DE. Understanding and Using DICOM, the Medical Image Communication Standard. JAMIA. 1997; 4:199-212.
  5. Bidgood WD, alSafadi Y, Tucker M, Prior FW, Hagan G,  Mattison JE. The Role of DICOM in an Evolving Healthcare Computing Environment: The Model is The Message. J Digit Imaging. 1998; 11(1):1-9.
  6. Coates TD, Larson-Prior L, Wolpert S, Prior FW. Classification of Simple Stimuli Based on Detected Nerve Activity. IEEE Eng Med Biol. 2003; 22(1):64-76. PMID: 12683065
  7. Falk D, Hildeboldt C, Smith K, Morwood MJ, Sutikna T, Brown P, Brunsden B, Prior FW.  The Brain of LB1, Homo floresiensis.  Science 2005 308(5719):242-5. PMID: 15749690
  8. Clark KW, Gierada DS, Moore SM, Maffitt DR, Koppel P, Phillips SR, Prior FW. Creation of a CT Image Library for the Lung Screening Study of the National Lung Screening Trial, Journal of Digital Imaging, 2007, 20(1): 23-31. PMID: 16783598
  9. Mun, SK, Prior, F., Caramella D, Ratib O. Introduction to the Special Section on Image Management in the Healthcare Enterprise, IEEE Trans. Info. Tech. in Biomed. 2007; 11(1):1-6. PMID: 17249397
  10. Falk D, Hildeboldt C, Smith K, Morwood MJ, Sutikna T, Saptomo E, Imhof H, Seidler H, Prior FW.  Brain Shape in Human Microcephalics and Homo floresiensis.  PNAS 2007; 104(7):2513-2518. PMCID: PMC1892980
  11. Prior F, Erickson B, Tarbox L. Open Source Software Projects of the caBIG™ In Vivo Imaging Workspace Software Special Interest Group.  Journal of Digital Imaging, 2007; 20(supl 1):94-100, doi: 10.1007/s10278-007-9061-4. PMCID: PMC2039820
  12. Vendt B, McKinstry R, Ball, W Kraut M, Prior F, DeBaun M. Silent Cerebral Infarct Transfusion (SIT) Trial Imaging Core: Application of Novel Imaging Information Technology for Rapid and Central Review of MRI of the Brain.  Journal of Digital Imaging, 2009; 22(3):326-343, DOI: 10.1007/s10278-008-9114-3. PMCID: PMC2801625
  13. Erinjeri  JP, Picus D, Prior F, Rubin D,  Koppel P, Development of a Google-Based Search Engine for Data Mining Radiology Reports.  Journal of Digital Imaging, 2009; 22(4):348:356, doi: 10.1007/s10278-008-9110-7. PMID: 18392657
  14. Hastings M,  Gelber J, Commean P, Prior F, Sinacore D, Bone Mineral Density of the Tarsals and Metatarsals with Reloading.  Physical Therapy, 2008; 88(6):1-13, doi: 10.2522/ptj.20070226. PMCID: PMC2409979
  15. Clark K, Gierada D, Marquez G, Moore S, Maffitt D, Moulton J, Wolfsberger M, Koppel P, Phillips S, Prior F, Collecting 48,000 CT Exams for the Lung Screening Study of the National Lung Screening Trial. Journal of Digital Imaging, 2009; 22(6):667-680, DOI 10.1007/s10278-008-9145-9. PMID: 18777192
  16. Prior F,  Brunsden B,  Hildebolt C, Nolan T, Pringle M, Vaishnavi SN, Larson-Prior, L, Facial Recognition from Volume Rendered Magnetic Resonance Imaging Data. IEEE Trans. Inf. Tech. Biomed, 2009; 13(1):5-9. PMID: 19129018
  17. Prior F, Medical Knowledge Discovery and Management. Mil Med 2009; 174 (5) (Suppl): 21-26. PMID: 19562958
  18. Falk D, Hildeboldt C, Smith K, Jungers W, Larson S, Morwood M, Sutikna T, Jatmiko, Saptomo E, Prior F.  The Type Specimen (LB1) of Homo floresiensis Did Not Have Laron Syndrome. Am J Phy Anthro. 2009; 140(1):52-63. DOI: 10.1002/ajpa.21035. PMID: 19294744
  19. Larson-Prior L, Zempel J, Nolan T, Prior F, Snyder A, Raichle M, Cortical network functional connectivity in the descent to sleep. PNAS 2009; 106(11): 4489-4494, doi: 10.1073/pnas.0900924106. PMCID: PMC2657465
  20. Falk D, Hildebolt C, Smith K, Morwood M.J., Sutikna T, Jatmiko, Saptomo E, Prior F, LB1's virtual endocast, microcephaly, and hominin brain evolution, Journal of Human Evolution, 2009; 57(5):597-607, doi: 10.1016/j.jhevol.2008.10.008. PMID: 19254807 
  21. Cholleti S, Goldman S, Blum A, Politte D, Don S, Smith K, Prior F, VERITAS: Combining Expert Opinions Without Labeled Data.  International Journal on Artificial Intelligence Tools, 2009; 18(5):633-651.
  22. Chen J, Wong S, Chang J, Chung P, Li H, Koc U, Prior F, Newcomb R.  Wake-up Call for the Engineering and Biomedical Science Communities - Major Challenges in Biomarker Development and Application, IEEE Circuits and Systems, 2009; 9(2):69-77, doi:10.1109/MCAS.2009.932557.
  23. Prior F, Commean P, Ju T, Hastings M, Hildebolt C, Sinacore D. Developing a Biomarker for Neuropathic Arthropathy in Diabetic Patients.  IEEE/NIH Life Science Systems and Applications Workshop, 2007; 13-16. IEEE Xplore DOI 10.1109/LSSA.2007.4400873
  24. Liu L, Raber D, Nopachai D, Commean P, Sinacore D, Prior F, Pless R, Ju T. Interactive Separation of Segmented Bones in CT Volumes using Graph Cut,  Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008 2008;52411(Pt 1):296-304. PMID: 18979760
  25. Prior F, Ingeholm M, Levine B, Tarbox L.  Potential Impact of HITECH Security Regulations on Medical Imaging.  IEEE EMBS Conf. 2009, 2157-2160. IEEE Xplore, DOI 10.1109/IEMBS.2009.5332507. PMID: 19963534
  26. Levine B, Ingeholm M, Prior F, Mun S, Freedman M, Weissman D, Attfield M, Wolfe A, Petsonk E,  Conversion to use of Digital Chest Images for Surveillance of Coal Workers’ Pneumoconiosis (Black Lung). IEEE EMBS Conf. 2009, 2161–2163. IEEE Xplore,  DOI 10.1109/IEMBS.2009.5332422. PMID: 19963535
  27. Philbin J, Prior F., Nagy P. Will the next generation of PACS be sitting on a cloud? Journal of Digital Imaging, 2010, DOI: 10.1007/s10278-010-9331-4.
  28. Politte D, Prior F, Ponton C, Nolan T, Larson-Prior L, Sources of non-physiologic noise in simultaneous EEG-fMRI data: a phantom study. IEEE EMBS Conf. 2010, 5129-5132. IEEE Xplore, DOI 10.1109/IEMBS.2010.5626168. PMID: 21095809.
  29. Rhodes C, Moore S, Clark K, Maffitt D, Perry J, Handzel T, Prior F, Regulatory Compliance Requirements for an Open Source Electronic Image Trial Management System. IEEE EMBS Conf. 2010, 3475-3478. IEEE Xplore, DOI 10.1109/IEMBS.2010.5627838. PMID: 21097264