Thomas K. Pilgram, Ph.D. is an Instructor of Radiology at the Mallinckrodt Institute of Radiology, Washington University in Saint Louis School of Medicine. Dr. Pilgram has 25 years experience in the use of statistics to further scientific research. He has worked in a variety of fields, including anthropology, archaeology, and wildlife biology, but the bulk of his experience has been in radiology research. He has held teaching positions at United States International University – Africa, University of California, Berkeley, and Washington University in Saint Louis, and has been on the faculty of the Washington University School of Medicine for the last 15 years.

Dr. Pilgram’s biostatistical work at the Mallinckrodt Institute of Radiology covers a wide range of topics, but recently has been concentrated in three areas with long-term funding: the relationship between orthosis design and plantar pressure in the diabetic foot, monitoring reader performance in the National Lung Screening Trial, and predicting the stability of coronary plaque. In addition to these large projects, Dr. Pilgram’s consulting work within the Institute contributes to a number of smaller projects. These include: interventional radiology, typically using survival analysis to measure the success of procedures, children’s craniofacial surgery, evaluating the success of techniques designed to correct birth defects, and electronic radiology, helping determine the requirements of diagnostically useful image display and transmission techniques. One of his specialties is small-sample statistics, which is especially useful in pilot studies.

1. Hovsepian DV, Ratts VS, Rodriguez M, Huang JS, Abuchon MG, Pilgram TK. A prospective comparison of the impact of uterine artery embolization, myomectomy, and hysterectomy on ovarian function. Journal of Vascular and Interventional Radiology 2006; 17:1111-1115.
2. Actis RL, Ventura LB, Smith KE, Commean PK, Lott DJ, Pilgram TK, Mueller MJ. Numerical simulation of the plantar pressure distribution in the diabetic foot during the push-off stance. Medical & Biological Engineering & Computing 2006; 44:653-663.
3. Gibson JE, PilgramTK, Gilula LA. Response of nonmidline pain to percutaneous vertebroplasty. American Journal of Roentgenology 2006; 187:869-872.
4. Elsayed AA, Moran CJ, Cross DT 3rd, Derdeyn CP, Pilgram TK, Milburn JM, Dacey RG Jr, Diringer MN Jr. Effect of intraarterial papaverine and/or angioplasty on the cerebral veins in patients with vasospasm after subarachnoid hemorrhage due to ruptured intracranial aneurysms. Neurosurgical Focus 2006; 21(3):E16.
5. Gierada DS, Pilgram TK, Hong C, Bierhals AJ, Kim JH, Bae KT. Comparison of standard- and low-radiation-dose CT for quantification of emphysema. American Journal of Roentgenology 2007; 188:42-47.
6. Hastings MK, Mueller MJ, Pilgram TK, Lott DJ, Commean PK, Johnson JE. Effect of metatarsal pad placement on plantar pressure in people with diabetes mellitus and peripheral neuropathy. Foot & Ankle International 2007; 28:84-88.
7. Wiggins MC, Sehizadeh M, Pilgram TK, Gilula LG. Importance of intravertebral fracture clefts in vertebroplasty outcome. American Journal of Roentgenology 2007; 188:643-640.
8. Schmelzer RE, Perlyn CA, Kane AA, Pilgram TK, Govier D. Identifying reproducible patterns of calvarial dysmorphology in nonsyndromic sagittal craniosynostosis may affect operative intervention and outcomes assessment. Plastic and Reconstructive Surgery 2007; 119:1546-1452.
9. Ho AS, Picus J, Darcy MD, Tan B, Gould JE, Pilgram TK, Brown DB.  Long-term outcome after chemoembolization of hepatic metastatic lesions from neuroendocrine tumors. American Journal of Roentgenology 2007; 188:1201-1207.
10. Yamada NC, Cross DT 3rd, Pilgram TK, Moran CJ, Derdyn CP, Dacey RG jr. Effect of antiplatelet therapy on thromboembolic complications of elective coil embolization of cerebral aneurysms. American Journal of Neuroradiology 2007; 28:1778-1782.
11. Rivet DJ, Moran CJ, Mazumdar A, Pilgram TK, Derdyn CP, Cross DT. Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. American Journal of Neuroradiology 2007; 28:1736-1742.
12. Gierada DS, Pilgram TK, Ford M, Fagerstrom RM, Church TR, Nath H, Garg K, Strollo DC. Lung cancer: interobserver agreement on interpretation of pulmonary findings at low-dose CT screening. Radiology 2008; 246:265-72.
13. Sharma KV, Gould JE, Harbour JW, Linette JP, Pilgram TK, Jayani PN, Brown DB. Hepatic arterial chemoembolization for management of metastatic melanoma. American Journal of Roentgenology. 2008; 190:99-104.
14. Vesely TM, Amin MZ, Pilgram T. Use of stents and stent grafts to salvage angioplasty failures in patients with hemodialysis grafts. Seminars in Dialysis 2008; 21:100-104.
15. Brown DB, Chapman WC, Cook RD, Kerr JR, Gould, JE, Pilgram TK, Darcy MD. Chemoembolization of hepatocellular carcinoma: patient status at presentation and outcome over 15 years at a single center.  American Journal of Roentgenology 2008; 190:608-615.
16. Rossel S, Marshall F, Peters J, Pilgram T, Adams MD, O’Connor D. Domestication of the donkey: timing processes, and indicators.  Proceedings of the National Academy of Sciences 2008; 105:3715-3720.
17. Marionneau C, Brunet S, Flagg TP, Pilgram TK, Demolombe S, Nerbonne JM. Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy. Circulation Research 2008; 102:1406-1415. (Subject of editorial: Nattel S. Effects of heart disease on cardiac ion current density versus current amplitude: important conceptual subtleties in the language of arrhythmogenic ion channel remodeling. Circulation Research 2008; 102:1298-1300.)
18. Fowler EA, Backer DB, Pilgram TK, Noetzel M, Epstein J, Kand AA. Neurologic findings in infants with deformational plagiocephaly. Journal of Child Neurology 2008; 23:742-747.
19. Lutey BA, Lefrak SS, Woods JC, Tanoli T, Quirk JD, Bashir A, Yablonskiy DA, Conradi MS, Bartel ST, Pilgram TK, Cooper JD, Gierada DS. Hyperpolarized 3He MR imaging: physiologic monitoring observations and safety considerations in 100 consecutive subjects. Radiology 2008; 248:655-661.
20. Pflederer TA, Kwok S, Ketel BL, Pilgram T. A comparison of transposed brachiobasilic fistulae with nontransposed fistulae and grafts in the fistula first era. Seminars in Dialysis 2008; 21:357-363.
21. Hong D, Heiken JP, Sicard GA, Pilgram TK, Bae KT. Clinical significance of endoleak detected on follow-up CT after endovascular repair of abdominal aortic aneurysm. American Journal of Roentgenology 2008; 191:808-813.
22. Balci NC, Befeler AS, Leiva P, Pilgram TK. Havlioglu N. Imaging of liver disease: comparison between quadruple-phase multidetector computed tomography and magnetic resonance imaging. Journal of Gastroenterology and Hepatology 2008;
23. Stuart JE, Tan B, Myerson RJ, Garcia-Ramirez J, Goddu SM, Pilgram TK, Brown DB. Salvage Radioembolization of liver-dominant metastases with a resin-based microsphere: initial outcomes. Journal of Vascular and Interventional Radiology 2008; 19:1427-1433.
24. Tao C, Gierada DS, Zhu F, Pilgram TK, Wang JH, Bae KT. Automated matching of pulmonary nodules: evaluation in serial screening chest CT. American Journal of Roentgenology 2009;192:624-628.
25. Sharma A, Pilgram T, Wippold FJ 2nd. Association between annular tears and disc degeneration: a longitudinal study. American Journal of Roentgenology 2009; 30:500-506.